Sunday, February 11, 2007

Recent tests have shown that an inexpensive drug may be able to kill cancer cells in humans. Dichloroacetate, a drug generally used to treat rare metabolic disorders, has shown the potential to assist in the treatment of brain, lung, and breast cancers, researchers at the University of Alberta in Edmonton, Canada say.

Dr. Evangelos Michelakis of the University of Alberta in Edmonton, Canada found that that DCA causes tumor regressions in animals with human cancers. Testing showed that DCA attacked cancer cells but did not attack healthy cells.

The researchers and the Alberta Cancer Board and Capital Health do not advise the use of DCA to treat cancer yet, as clinical trials for the drugs use to treat cancer have not been performed yet.

Unlike healthy cells, cancerous cells do not convert food molecules into energy in the mitochondria. Instead, they rely on a process known as glycolysis, which takes place in the main body of the cell, while the mitochondria are “shut down”, researchers believe possibly due to the lack of oxygen supply to cells in the middle of a tumor.

This means that another key function of the mitochondria – to activate an abnormal cell’s self-destruct mechanism, apoptosis – is also blocked.

When Dichloroacetate (DCA) enters a cancer cell, it restarts the mitochondria which in turn activate apoptosis, and the cancerous cell destroys itself.

DCA is known to be relatively safe, although pain, numbness and gait disturbances may occur. The drug is also expected to be cheaper to manufacture than other drugs since there is no patent for it.

Friday, May 11, 2007

At least two Kentucky Fried Chicken [KFC] restaurants, operated by G & H Restaurant Specialties, have closed in Buffalo, New York “for remodeling,” according to signs placed on the front doors of at least one location on Elmwood Avenue and Bryant Street in Buffalo. The other KFC is located on East Delavan Avenue, also in the City of Buffalo.

Despite the claim of closing for remodeling, the Erie County Health Department says that several health code violations were found at both locations. The most recent violation was logged by the health department in March at the Elmwood location for failing to keep food stored at correct temperatures. Violations were also cited for failing to keep cooking supplies and equipment sanitary and for not supplying hot water to the bathroom for employees.

G & H Restaurant Specialties has not released a statement regarding the violations, but the corporate offices in Louisville, Kentucky for KFC said, “our franchisee has finalized a plan for some structural repairs… The units will be temporarily closed while these building maintenance issues are addressed. [They will be] re-opened as soon as the repairs are complete.”

The health department also gave violations out to the East Delevan store for failing to maintain a clean floor throughout the restaurant and for not stopping food from becoming contaminated. Several rat traps were also found inside the storage cooler and around the kitchen area, but the establishment was “not free of rodents,” said Commissioner of the Erie County Health Department, Dr. Anthony Billittier.

Billittier also said that caulking and traps were seen on the outside of the East Delevan restaurant, which was an attempt to keep the rats out. “It shows that they’re trying to take care of a problem. But it also shows that they have a problem.”

As of Thursday, May 10, 2007, the Elmwood KFC has yet to reopen. It is not known if the East Delevan location opened today or not.

Friday, March 30, 2007

Dell Inc., a global leader in computer hardware manufacturing and sales, announced yesterday that it will delay filing of its annual performance report, the Form 10-K, required for compliance with U.S. Securities and Exchange Commission (SEC) and Nasdaq listing rules.

In a press release, Dell explained that an audit committee of the company’s board of directors is carrying out an investigation into accounting and financial reporting issues. The company stated that it would delay filing of the 10-K since the investigation had not been completed.

The internal investigation has found evidence of accounting errors, misconduct, and deficiencies in areas of financial control.

The chairman of Dell’s audit committee, Thomas Luce III, indicated that the delay in filing would extend past the April 3, 2007 deadline as well as an April 18, 2007 extension date. “As we move toward the conclusion of our investigation, we are committing the time and resources required to ensure a thorough and comprehensive review and resolution of all identified issues and the implementation of appropriate remedial measures,” said Luce.

The investigation is to determine whether the restatement of any financial disclosures are warranted, based on the accounting errors identified. The probe will also assess whether there are deficiencies in Dell’s internal control over financial reporting.

Friday, May 26, 2006

After approximately 150 Australian troops from 4 Royal Australian Regiment (Commandos) secured Comoro airport in Dili yesterday, the total number of Australian troops in East Timor has risen to 600, with a further 1200 in transit or directly supporting Operation Astute. Malaysia, New Zealand and Portugal have also begun their deployments. Malaysia has now sent 25 military officers ahead of its 500 strong commitment of military and police personnel; New Zealand has committed two C-130s, and an infantry company is on standby pending negotiations over rules of engagement; Portugal’s 120-strong commitment has commenced preparations, but is not expected to arrive for a matter of weeks. The Australian contingent involved in Operation Astute has been placed under the command of Brigadier Michael Slater, who arrived in Dili this morning.

Currently, the Australian Department of Defence states Operation Astute’s tasks are:

1. to facilitate the evacuation of Australian and other foreign nationals as is appropriate and necessary;
2. to stabilise the situation and facilitate the concentration of the various conflicting groups into safe and secure locations;
3. to audit and account for the location of weapons that belong to each group; and
4. to create a secure environment for the conduct of a successful dialogue to resolve the current crisis.

Australian forces are already actively operating in Dili; Infantry patrols are operating in the area, supported by the four Blackhawks from the 5th Aviation Regiment that have arrived so far. Blackhawks have also been operating missions above the hills around Dili to seek out rebel positions and communicate a strong presence to the rebel soldiers. Two Armoured Personnel Carriers and an infantry platoon have set up position in and around the UN Headquarters and Dili police station, which came under attack earlier today, and was the location of considerable violence yesterday when East Timorese army soldiers killed 12 East Timorese police and wounded numerous others, including 2 UN personnel. “At the moment things are relatively stable, the troops are arriving and we are establishing good control throughout the Dili area” BRIG Slater said of the situation.

Yesterday 80 Australian nationals were evacuated by RAAF C-130, a number that is rising as flights in and out of East Timor have been unhampered since the securing of Comoro airport. Approximately 800 Australian nationals were in East Timor at the beginning of conflict.

Events involving East Timor’s government are complicating the situation. Reports state that Prime Minister Mari Alkatiri is reluctant to allow foreign troops to independently operate in the country and arguing with President Xanana Gusmao over who should control the small nation’s still loyal military of 800 troops. After President Gusmao declared he had taken over command of the military and ordered all East Timorese military personnel to barracks, Alkatiri stated that he believed the President does not have a constitutional right to take control of the military, as that depends on a ‘situation of emergency’ being declared, which is itself dependent on the parliament.

According to Mark Thompson, a military budgeting specialist from the Australian Strategic Policy Institute, Operation Astute would cost a similar amount to Australia’s earlier peacekeeping operation in East Timor – approximately $200 million.

Wednesday, November 6, 2013

This week, Wikinews interviewed Spanish Paralympic sport shooter Paulo Fontán Torreiro. Late last month, Galician Fontán competed at the Alicante hosted 2013 IPC European Shooting Championship, where he finished twenty-third in the R4 10-meter air rifle standing event, and fortieth in the R5 10-meter air rifle prone event.

((Wikinews)) : So you competed at the IPC European Shooting Championships last month? How did you do? Are you happy with the result? ^{((es))Spanish language: ?¿Compitió en el pasado Campeonato de Europa de Tiro? ¿Qué tal le fue? ¿Satisfecho por el resultado?}

Paulo Fontán Torreiro: Yes, I competed in the European Championship in Alicante. It was my first important event and I felt very nervous, I wanted to perform well. Despite improving my previous scores and achieving the minimum qualifying score for next year’s World Championship, I think I could have done better. ^{((es))Spanish language: ?Si he competido en el cto de Europa de Alicante. Era mi primer campeonato de tanta importancia y me noté bastante nervioso, con ganas de hacerlo bien. Aunque he mejorado mis marcas anteriores y he conseguido las marcas mínimas para tener la posibilidad de participar en el campeonato del mundo del año que viene, si es cierto que considero que lo debí haber hecho algo mejor.}

((WN)) : What do you think you need to improve to possibly compete at the 2016 Rio Paralympics and get a medal? ^{((es))Spanish language: ?¿Qué cree que necesita mejorar para poder competir en los Juegos Paralímpicos de Rio en 2016 y ganar una medalla?}

Paulo Fontán: Basically I would need to be able to train more constantly, obtain financial resources to participate in international events, and have a bit of luck on the day of the competition. ^{((es))Spanish language: ?Fundamentalmente necesitaría poder entrenar con más constancia, conseguir recursos económicos para poder participar en competiciones internacionales y despues tener algo de suerte el día de la competición.}

((WN)) : What are the biggest challenges you face on the road to the Rio Games? Money? Good competition? The support network to travel and compete at the highest level? Disability access at training venues? ^{((es))Spanish language: ?¿Cuáles son los mayores desafíos a los que se enfrenta en el camino a los Juegos de Rio? ¿Presupuesto? ¿Buenos rivales para aumentar su nivel? ¿Una red de apoyo para viajar y competir al máximo nivel? ¿Acceso para discapacitados en lugares de entrenamiento?}

Paulo Fontán: All that are included in the questions. In order to train effectively, you need adequate facilities, and that’s not the norm here. And to increase my level, I would need to compete against good rivals, basically at international events. For that, I require money and support, something that’s not too available. ^{((es))Spanish language: ?Pues todos los que aparecen en las preguntas. Para entrenar con garantías hace falta contar con instalaciones adecuadas, y no es lo habitual. Y para mejorar mi nivel necesitaría competir con buenos rivales (basicamente en competiciones internacionales) y para ello hace falta dinero y apoyos, algo que escasea.}

((WN)) : Why did you chose to compete in shooting? Why not compete in another sport? ^{((es))Spanish language: ?¿Por qué eligió competir en tiro? ¿Por qué no otro deporte?}

Paulo Fontán: I first tried other sports but finally focused on shooting because it fits my capabilities better, I’m not bad at it, and there is a very agreeable atmosphere at the competitions. ^{((es))Spanish language: ?Probé primero otros deportes pero finalmente me he centrado en el tiro porque se ajusta mejor a mis capacidades, no se me da mal y he respirado un ambiente muy agradable en las competiciones.}

((WN)) : Who are your role models in shooting? Are there any shooters you particularly admire? ^{((es))Spanish language: ?¿Quién es su modelo a seguir en tiro? ¿Existen tiradores/as a los que particularmente admire?}

Paulo Fontán: I must thank the support Juan Saavedra has given me since I started, and which he keeps giving me when I need it. I would like to mention Marciano Vázquez, the Spanish national team coach, too for his advice and trust in me when he called me up for the European Championship: I hope to return his trust with some future triumph. ^{((es))Spanish language: ?Tengo que agradecer el apoyo que siempre me ha brindado Juan Saavedra desde que empecé, y que me sigue brindando cuando lo necesito. Citar también a Marciano Vázquez, seleccionador nacional de Tiro Olímpico, por sus consejos y por su confianza en mi persona a la hora de convocarme para el cto de Europa; espero poder devolverle la confianza con algún éxito futuro.}

((WN)) : What is the sport shooting culture like in Spain? Are people generally supportive when you tell them what sport you compete in? ^{((es))Spanish language: ?¿Cómo es recibido este deporte culturalmente en España? ¿La gente le apoya cuando dice que es tirador?}

Paulo Fontán: I don’t think it’s very well known, and there could be some rejection because of the “pegar tiros” part, but that’s out of ignorance since it is mainly a mental sport, a sport requiring focus. ^{((es))Spanish language: ?Creo que no es muy conocido y quizá pueda haber cierto rechazo por eso de “pegar tiros” pero es fruto del desconocimiento ya que fundamentaolmente es un deporte mental, de concentración.}

((WN)) : Do you think the classification system in shooting is fair? Do you think it should be changed? ^{((es))Spanish language: ?¿Piensa que el sistema de clasificación en tiro es justo? ¿Piensa que se debería cambiar?}

Paulo Fontán: I’ve only been doing this for three years and haven’t had time to analyze it deeply so as to have an opinion about it. ^{((es))Spanish language: ?Llevo sólo tres años y no he tenido tiempo de analizarlo en profundidad como para tener una opinión al respecto.}

((WN)) : Would you recommend the sport to other people with disabilities? What are reasons they should or should not take up the sport? ^{((es))Spanish language: ?¿Recomendaría este deporte a otras personas con discapacidad? ¿Cuáles son las razones por las que deberían -o no deberían- practicar este deporte?}

Paulo Fontán: Yes, I would recommend it, and I would because it is a sport which can be practiced by a wide array of different disabilities, and for a long time. The biggest problem is the high initial investment, the lack of adequate facilities or the cost of travelling to competitions since there are not many places that allow people with disabilities to participate. ^{((es))Spanish language: ?Si lo recomendaría, y lo recomiendo porque es un deporte que se pude practicas por una gran diversidad de discapacidades diferentes, y durante mucho tiempo. El mayor problema es la elevada inversión inical, la ausencia de infraestructuras adecuadas o el coste de los desplazamientos a las competiciones (ya que no hay muchas en las que permitan participar a personas con discapacidad).}

Friday, December 12, 2008

Top broker and Wall Street adviser Bernard L. Madoff, aged 70, was arrested and charged by the FBI on Thursday with a single count of securities fraud, also known as stock fraud and investment fraud. He allegedly told senior employees of his firm on Wednesday that his $50 billion business “is all just one big lie” and that it was “basically, a giant Ponzi scheme (since at least 2005).” Mr. Madoff faces up to 20 years imprisonment and a fine of up to $5 million. FBI agent Theodore Cacioppi said Mr. Madoff’s investment advisory business had “deceived investors by operating a securities business in which he traded and lost investor money, and then paid certain investors purported returns on investment with the principal received from other, different investors, which resulted in investors’ losses of approximately $50 billion dollars.”

The former chairman of the Nasdaq Stock Market is also the founder and primary owner of Bernard L. Madoff Investment Securities LLC, the closely-held market-making firm he launched in 1960. The firm is one of the top market maker firms on Wall Street. He founded his family firm with an initial investment of $5,000, after attending Hofstra University Law School. He saved the money earned from a job lifeguarding at Rockaway Beach in Queens and a part time job installing underground sprinkler systems.

A force in Wall Street trading for nearly 50 years, he has been active in the National Association of Securities Dealers (NASD), a self-regulatory organization for the U.S. securities industry. His firm was one of the five most active firms in the development of the NASDAQ, having been known for “paying for order flow,” in other word paying a broker to execute a customer’s order through Madoff. He argued that the payment to the broker did not alter the price that the customer received. He ran the investment advisory as a secretive business, however.

Dan Horwitz, counsel of Mr. Madoff, in an interview, said that “he is a longstanding leader in the financial-services industry with an unblemished record; he is a person of integrity; he intends to fight to get through this unfortunate event.” Mr. Madoff was released on his own recognizance on the same day of his arrest, after his 2 sons turned him in, and posting $10 million bail secured by his Manhattan apartment. Without entering any plea, the Court set the preliminary hearing for January 12.

Madoff’s hedge fund scheme may rank among the biggest fraud in history. When former energy trading giant Enron filed for bankruptcy in 2001, one of the largest at the time, it had $63.4 billion in assets. The scheme would dwarf past Ponzis, and it would further be nearly five times the telecommunication company WorldCom fraud and bankruptcy proceedings in 2002.

The Securities and Exchange Commission filed a separate civil suit on Thursday against Bernard L. Madoff Investment Securities and its eponymous founder Mr. Madoff. It was docketed as “U.S. v. Madoff,” 08-MAG-02735, by the U.S. District Court for the Southern District of New York (Manhattan). SEC, New York associate director of enforcement, Andrew M. Calamari, asked the judge to issue seizure orders on the firm and its assets, and appoint a receiver. The SEC pleads, among others, that “it was an ongoing $50 billion swindle; our complaint alleges a stunning fraud that appears to be of epic proportions.” It further accused the defendant of “paying returns to certain investors out of the principal received from other, different investors” for years. Madoff’s hedge fund business had previously claimed to have served between 11 and 25 clients and had $17.1 billion in assets under management. But virtually all of the assets were missing.

United States District Court for the Southern District of New York Louis L. Stanton on Thursday appointed Lee Richards, a Manhattan lawyer, as the firm’s receiver. A hearing is set for Friday, for a ruling on the SEC’s petition to grant plenary powers to the receiver over the entire firm, and an absolute asset sequestration.

Doug Kass, president of hedge fund Seabreeze Partners Management said that “this is a major blow to confidence that is already shattered — anyone on the fence will probably try to take their money out.”

Thursday, October 22, 2020

2020 Melbourne Lord Mayor candidate Wayne Tseng answered some questions about his campaign for the upcoming election from Wikinews. The Lord Mayor election in the Australian city is scheduled to take place this week.

Tseng runs a firm called eTranslate, which helps software developers to make the software available to the users. In the candidate’s questionnaire, Tseng said eTranslate had led to him working with all three tiers of the government. He previously belonged to the Australian Liberal Party, but has left since then, to run for mayorship as an independent candidate.

Tseng is of Chinese descent, having moved to Australia with his parents from Vietnam. Graduated in Brisbane, Tseng received his PhD in Melbourne and has been living in the city, he told Wikinews. Tseng also formed Chinese Precinct Chamber of Commerce, an organisation responsible for many “community bond building initiatives”, the Lord Mayor candidate told Wikinews.

Tseng discussed his plans for leading Melbourne, recovering from COVID-19, and “Democracy 2.0” to ensure concerns of minorities in the city were also heard. Tseng also focused on the importance of the multi-culture aspect and talked about making Melbourne the capital of the aboriginals. Tseng also explained why he thinks Melbourne is poised to be a world city by 2030.

Tseng’s deputy Lord Mayor candidate Gricol Yang is a Commercial Banker and works for ANZ Banking Group.

Currently, Sally Capp is the Lord Mayor of Melbourne, the Victorian capital. Capp was elected as an interim Lord Mayor in mid-2018 after the former Lord Mayor Robert Doyle resigned from his position after sexual assault allegations. Doyle served as the Lord Mayor of Melbourne for almost a decade since 2008.